Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20792451 | 0.91 | KMT2A (0.55) | KMT2AMEN1GAAACHENPSR1 | |
| SCHEMBL20327220 | 0.85 | KMT2A (0.41) | KMT2AMEN1GAATAS1R3TAS1R1 | |
| SCHEMBL21667311 | 0.79 | PARP1 (0.42) | KMT2AMEN1GAAACHEFURIN | |
| SCHEMBL26017812 | 0.78 | ACSS2 (0.41) | KMT2AMEN1TAS1R3TAS1R1ACHE | |
| SCHEMBL25020982 | 0.78 | MEN1 (0.33) | KMT2AMEN1GAAACHENPSR1 | |
| SCHEMBL19726233 | 0.78 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL28861776 | 0.78 | MEN1 (0.49) | KMT2AMEN1GAAFURINALDH1A1 | |
| SCHEMBL28230918 | 0.78 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL24625373 | 0.77 | AKR1C3 (0.36) | KMT2AMEN1GAAFURIN | |
| SCHEMBL22628277 | 0.77 | AKR1C3 (0.36) | KMT2AMEN1GAAFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219493-A1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| EP-3728254-B1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-02-15 | — | — | EP | disclosed |