Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25020739 | 0.92 | KRAS (0.55) | KRAS | |
| SCHEMBL25020049 | 0.91 | KRAS (0.54) | KRAS | |
| SCHEMBL25019983 | 0.91 | KRAS (0.54) | KRAS | |
| SCHEMBL21846414 | 0.91 | KRAS (0.56) | KRAS | |
| SCHEMBL25020791 | 0.91 | KRAS (0.54) | KRAS | |
| SCHEMBL22010331 | 0.90 | KRAS (0.47) | KRAS | |
| SCHEMBL22010611 | 0.90 | KRAS (0.47) | KRAS | |
| SCHEMBL22725400 | 0.90 | KRAS (0.57) | KRAS | |
| SCHEMBL25021744 | 0.89 | KRAS (0.52) | KRAS | |
| SCHEMBL22010434 | 0.88 | KRAS (0.47) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |