Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133179 | 1.00 | HTR2A (0.45) | HTR2AHTR2CHTR2BTAAR1SLC6A2 | |
| SCHEMBL14120621 | 0.85 | PTPN5 (0.43) | HTR2AHTR2CHTR2BSLC6A4SIGMAR1 | |
| SCHEMBL18266583 | 0.85 | HTR2A (0.41) | HTR2AHTR2CHTR2BTAAR1SLC6A2 | |
| SCHEMBL14259225 | 0.82 | HTR2A (0.41) | HTR2AHTR2CHTR2BTAAR1SLC6A4 | |
| SCHEMBL11414162 | 0.80 | HTR2A (0.64) | HTR2AHTR2CHTR2BTAAR1SLC6A2 | |
| SCHEMBL28644938 | 0.79 | TAAR1 (0.42) | HTR2AHTR2CHTR2BTAAR1SLC6A2 | |
| SCHEMBL20431924 | 0.78 | SLC22A1 (0.37) | HTR2AHTR2CHTR2BTAAR1SLC6A2 | |
| SCHEMBL24324366 | 0.78 | TAAR1 (0.41) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL29342899 | 0.77 | TAAR1 (0.43) | HTR2AHTR2CHTR2BTAAR1SLC6A2 | |
| SCHEMBL28856242 | 0.77 | PNMT (0.47) | TAAR1SLC6A2MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728254-B1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-02-15 | — | — | EP | disclosed |