SCHEMBL250204

SCHEMBL250204

O=P(O)(O)C(CC(P(=O)(O)O)P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FDPS P14324 6/20 0.50
KDM4E B2RXH2 1/20 0.44
MMP2 P08253 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ANPEP P15144 4/20 0.39
LAP3 P28838 3/20 0.39
ERAP1 Q9NZ08 1/20 0.39
TYMS P04818 1/20 0.39
ERAP2 Q6P179 1/20 0.38
GGPS1 O95749 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29449121 0.96 FDPS (0.48) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL8709594 0.96 FDPS (0.48) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL8713308 0.96 FDPS (0.48) FDPSKDM4EMMP2THRBMAPK1
Water SCHEMBL8015709 0.93 FDPS (0.46) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL20699852 0.83 FDPS (0.43) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL8709597 0.83 FDPS (0.39) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL12570892 0.81 ANPEP (0.56) FDPSANPEPLAP3ERAP1GGPS1
Water SCHEMBL8015711 0.81 FDPS (0.37) FDPSGGPS1
SCHEMBL9792344 0.78 FDPS (0.46) FDPSANPEPLAP3ERAP1GGPS1
SCHEMBL11333683 0.78 FDPS (0.46) FDPSANPEPLAP3ERAP1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP claimed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US claimed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US claimed
EP-1351722-B2 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2016-02-17 EP claimed
US-20140316533-A1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2014-10-23 US claimed
US-RE43793-E1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2012-11-06 US claimed
US-20120258148-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE (FR) 2012-10-11 US claimed
EP-1343545-B2 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2011-08-10 EP claimed
US-20100234900-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE 2010-09-16 US claimed
EP-0588229-A2 Macrocyclic chelating agents for the preparation of Technetium or Rhenium complexes CIS BIO INTERNATIONAL (FR) 1994-03-23 EP claimed
EP-0498333-A2 Preparation of an organospecific substance marked with technetium-99m CIS BIO INTERNATIONAL (FR) 1992-08-12 EP claimed
EP-0304780-B1 PROCESS FOR LABELLING SUBSTANCES WITH TECHNETIUM OR RHENIUM HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-07 EP claimed
EP-0304780-A1 Process for labelling substances with technetium or rhenium HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-01 EP claimed
EP-0271806-A2 Method for the preparation of a technetium-99m-labelled organ-specific substance HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-22 EP claimed
US-4693884-A NUCLEAR MEDICINE HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-15 US claimed
EP-0108253-B1 TECHNETIUM-99M-TETRAPHOSPHONATES FOR THE SCINTIGRAPHIC VISUALISATION OF THE R.E.S. ORGANS AND LYMPH VESSELS, AND PREPARATION PROCESS HOECHST AKTIENGESELLSCHAFT (DE) 1986-07-30 EP claimed
EP-0108253-A1 Technetium-99m-tetraphosphonates for the scintigraphic visualisation of the R.E.S. organs and lymph vessels, and preparation process HOECHST AKTIENGESELLSCHAFT (DE) 1984-05-16 EP claimed
US-4240920-A A SURFACTANT, A PEROXY BLEACH AND A PORPHINE BLEACH THE PROCTER & GAMBLE COMPANY (US) 1980-12-23 US claimed
US-RE29182-E POLYPHOSPHONIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 1977-04-12 US claimed