Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022706 | 0.99 | LMNA (0.40) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25022395 | 0.98 | HPGD (0.39) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25021573 | 0.89 | LMNA (0.42) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL20348340 | 0.84 | LMNA (0.39) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL20348337 | 0.83 | LMNA (0.39) | LMNAHPGDALDH1A1KDM4EPOLB | |
| SCHEMBL20348355 | 0.82 | LMNA (0.37) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25021356 | 0.81 | HPGD (0.38) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25021314 | 0.80 | EPHX1 (0.38) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25022263 | 0.79 | HPGD (0.38) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25021323 | 0.78 | LMNA (0.36) | LMNAHPGDL3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565410-B1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-02-15 | — | — | EP | disclosed |