Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25021303 | 0.94 | CYP3A4 (0.47) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL22567356 | 0.91 | CYP3A4 (0.49) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL24506756 | 0.91 | CYP3A4 (0.49) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL24101047 | 0.90 | LMNA (0.49) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL25021927 | 0.88 | CYP3A4 (0.48) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL24100695 | 0.87 | CYP3A4 (0.49) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL22567450 | 0.84 | LMNA (0.46) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| Melphalan Flufenamide SCHEMBL24101233 | 0.84 | LMNA (0.53) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| Melphalan Flufenamide SCHEMBL18239898 | 0.84 | LMNA (0.53) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| Melphalan Flufenamide SCHEMBL20208719 | 0.84 | LMNA (0.53) | CYP3A4KMT2AALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3866931-B1 | COMPOUNDS CONTAINING DEUTERIUM | ONCOPEPTIDES AB (SE) | 2023-02-15 | — | — | EP | disclosed |