SCHEMBL25022845

SCHEMBL25022845

Bc1cc(B2OC(C)(C)C(C)(C)O2)c(F)cc1N

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
JAK2 O60674 1/20 0.30
BTK Q06187 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19668082 0.90 LPL (0.38) LPLLIPGCA1CA2CA9
SCHEMBL59040 0.84 LPL (0.37) LPLLIPGJAK2BTK
SCHEMBL15289502 0.84 LPL (0.37) LPLLIPGJAK2BTK
SCHEMBL29385065 0.84 LPL (0.37) LPLLIPGJAK2BTK
SCHEMBL21067074 0.81 CYP3A4 (0.35) LPLLIPGJAK2BTK
SCHEMBL30316458 0.81 CYP3A4 (0.35) LPLLIPGJAK2BTK
SCHEMBL30935317 0.81 CYP3A4 (0.35) LPLLIPGJAK2BTK
SCHEMBL24457822 0.81 CYP3A4 (0.35) LPLLIPGJAK2BTK
SCHEMBL25277938 0.80 GAA (0.35) LPLLIPGJAK2BTK
SCHEMBL21067071 0.80 GAA (0.35) LPLLIPGJAK2BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134098-A1 METHOD OF CANCER THERAPY ONO Pharmaceutical Co., Ltd. (JP) 2023-02-15 EP disclosed