Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489342 | 0.80 | USP2 (0.44) | TSHRUSP2DPP7ALDH1A1LMNA | |
| SCHEMBL15613399 | 0.76 | KMT2A (0.43) | TSHRUSP2CYP2D6CA12CA9 | |
| SCHEMBL17662391 | 0.74 | SMN1; SMN2 (0.45) | CYP2D6ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL16317805 | 0.74 | PAOX (0.47) | TSHRDRD2DRD4DRD3CA12 | |
| SCHEMBL2461091 | 0.74 | DRD2 (0.41) | TSHRCYP2D6DRD2DRD4DRD3 | |
| SCHEMBL12387743 | 0.74 | KMT2A (0.42) | TSHRUSP2CYP2D6CA12CA9 | |
| SCHEMBL14108245 | 0.73 | USP2 (0.34) | TSHRUSP2CYP2D6CA12CA9 | |
| SCHEMBL24838593 | 0.73 | EPHX1 (0.57) | DPP7MMP8 | |
| SCHEMBL17663571 | 0.72 | KMT2A (0.54) | CYP2D6DRD2DRD4DRD3CA12 | |
| SCHEMBL16451032 | 0.72 | HPGD (0.47) | TSHRUSP2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018155-A1 | COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF | 주식회사 유빅스테라퓨틱스 | 2023-02-16 | — | — | WO | disclosed |