Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 14/20 | 0.47 |
| ▸ | JAK2 | O60674 | 13/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027523 | 1.00 | JAK3 (0.47) | JAK3JAK2PDCD1CD274PIK3CD | |
| SCHEMBL25028660 | 1.00 | JAK3 (0.47) | JAK3JAK2PDCD1CD274PIK3CD | |
| SCHEMBL29363962 | 1.00 | JAK3 (0.47) | JAK3JAK2PDCD1CD274PIK3CD | |
| SCHEMBL29361444 | 1.00 | JAK3 (0.47) | JAK3JAK2PDCD1CD274PIK3CD | |
| SCHEMBL29364416 | 1.00 | JAK3 (0.47) | JAK3JAK2PDCD1CD274PIK3CD | |
| SCHEMBL25028902 | 0.85 | BTK (0.44) | PDCD1CD274PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29362053 | 0.85 | BTK (0.44) | PDCD1CD274PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26719530 | 0.85 | JAK3 (0.44) | JAK3JAK2PDCD1CD274PIK3CD | |
| SCHEMBL25271983 | 0.84 | JAK3 (0.58) | JAK3JAK2 | |
| SCHEMBL25027630 | 0.84 | JAK3 (0.58) | JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | JAK3 1389/4885JAK2 3104/4885PDCD1 3460/4885 |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | JAK3 1262/4885JAK2 2900/4885PDCD1 3326/4885 |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | JAK3 1187/4885JAK2 3112/4885PDCD1 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.