Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028902 | 1.00 | BTK (0.44) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29364621 | 0.92 | BTK (0.43) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26719030 | 0.92 | BTK (0.43) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25028882 | 0.92 | BTK (0.43) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26717704 | 0.92 | BTK (0.43) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29361312 | 0.90 | BTK (0.42) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25029306 | 0.90 | BTK (0.42) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25029302 | 0.89 | BTK (0.41) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29363730 | 0.89 | BTK (0.41) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25029073 | 0.88 | BTK (0.41) | BTKPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |