SCHEMBL2502811

SCHEMBL2502811

CCCCC(CC)CNC(=O)C1CO1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 2/20 0.46
HTT P42858 3/20 0.44
GLA P06280 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA2 P00918 2/20 0.40
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28342466 0.81 TP53 (0.49) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL30958917 0.81 TSHR (0.48) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL16312309 0.76 TSHR (0.59) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL3966075 0.76 TSHR (0.59) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL5932194 0.74 TSHR (0.57) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL2105851 0.74 TSHR (0.57) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL1931195 0.74 TSHR (0.57) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL18638052 0.74 TSHR (0.57) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL16312317 0.74 TSHR (0.57) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL18627943 0.74 GNAI3 (0.46) TSHRALDH1A1CYP3A4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190322958-A1 Lubricant Composition BASF SE (DE) 2019-10-24 US disclosed
EP-2553059-B1 LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS CHEVRON ORONITE CO (US) 2019-10-23 EP disclosed
US-10066186-B2 Lubricating oil compositions containing a halide seal compatibility additive and a second seal compatibility additive BASF SE (DE) 2018-09-04 US disclosed
WO-2018089416-A1 LUBRICANT COMPOSITION BASF SE (DE) 2018-05-17 WO disclosed
US-9677023-B2 Lubricating oil compositions containing seal compatibility additives and sterically hindered amines BASF SE (DE) 2017-06-13 US disclosed
EP-3129454-A1 LUBRICATING OIL COMPOSITIONS CONTAINING SEAL COMPATIBILITY ADDITIVES AND STERICALLY HINDERED AMINES BASF SE (DE) 2017-02-15 EP disclosed
US-20170029737-A1 LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS BASF SE (DE) 2017-02-02 US disclosed
US-20160281024-A1 Method Of Forming Additive Packages and Lubricant Compositions That Include A Seal Compatibility Additive BASF SE (DE) 2016-09-29 US disclosed
US-9410105-B2 Lubricant compositions comprising epoxide compounds BASF SE (DE) 2016-08-09 US disclosed
US-20150291906-A1 Lubricating Oil Compositions Containing Seal Compatibility Additives And Sterically Hindered Amines BASF SE (DE) 2015-10-15 US disclosed
WO-2014078702-A1 LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY BASF SE (DE) 2014-05-22 WO disclosed
US-20140142010-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
WO-2014078691-A1 LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS BASF SE (DE) 2014-05-22 WO disclosed
US-20140142011-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
US-20140038869-A1 LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS CHEVRON ORONITE COMPANY LLC (US) 2014-02-06 US disclosed
US-20130281333-A1 LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS CHEVRON ORONITE COMPANY LLC (US) 2013-10-24 US disclosed
US-8486873-B2 Lubricating oil compositions containing epoxide antiwear agents CHEVRON ORONITE COMPANY LLC (US) 2013-07-16 US disclosed
EP-2553059-A2 LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS Chevron Oronite Company LLC (US) 2013-02-06 EP disclosed
WO-2011126636-A2 LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS CHEVRON ORONITE COMPANY LLC (US) 2011-10-13 WO disclosed
US-20110239969-A1 LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS CHEVRON ORONITE COMPANY LLC 2011-10-06 US disclosed