Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248489 | 1.00 | MAPT (0.35) | MAPTALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL25028043 | 0.88 | MAPT (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL30248562 | 0.88 | MAPT (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL29978483 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL23769463 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL25028042 | 0.79 | MAPT (0.48) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL29227011 | 0.79 | MAPT (0.48) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL29227188 | 0.79 | MAPT (0.48) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL30248409 | 0.79 | MAPT (0.48) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL29227209 | 0.79 | MAPT (0.48) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023017452-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |