Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 6/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.40 |
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL25247543 | 0.91 | GSK3B (0.43) | GSK3BDYRK1ANFATC1SLC6A4PIM1 | |
| Trifluoroacetic Acid SCHEMBL29363990 | 0.91 | GSK3B (0.43) | GSK3BDYRK1ANFATC1SLC6A4PIM1 | |
| SCHEMBL29363648 | 0.87 | GSK3B (0.52) | GSK3BDYRK1ANFATC1SLC6A4AR | |
| SCHEMBL29364138 | 0.87 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1SLC6A4AR | |
| SCHEMBL25027634 | 0.87 | GSK3B (0.52) | GSK3BDYRK1ANFATC1SLC6A4AR | |
| SCHEMBL25029164 | 0.87 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1SLC6A4AR | |
| SCHEMBL25028830 | 0.86 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1SLC6A4AR | |
| SCHEMBL29361163 | 0.85 | DYRK1A (0.50) | GSK3BDYRK1ANFATC1PIM1AR | |
| SCHEMBL25029034 | 0.85 | DYRK1A (0.50) | GSK3BDYRK1ANFATC1PIM1AR | |
| SCHEMBL26716362 | 0.84 | DYRK1A (0.49) | GSK3BDYRK1ANFATC1SLC6A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | GSK3B 463/4885DYRK1A 1187/4885NFATC1 1397/4885 |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | GSK3B 441/4885DYRK1A 1097/4885NFATC1 1359/4885 |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | GSK3B 468/4885DYRK1A 937/4885NFATC1 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.