Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 9/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027634 | 1.00 | GSK3B (0.52) | GSK3BDYRK1ANFATC1AREIF2AK2 | |
| SCHEMBL25029164 | 0.89 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL29364138 | 0.89 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL25028830 | 0.88 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL25028987 | 0.87 | GSK3B (0.50) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL29361163 | 0.87 | DYRK1A (0.50) | GSK3BDYRK1ANFATC1ARMEN1 | |
| SCHEMBL25029034 | 0.87 | DYRK1A (0.50) | GSK3BDYRK1ANFATC1ARMEN1 | |
| SCHEMBL26716362 | 0.86 | DYRK1A (0.49) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL29361365 | 0.85 | GSK3B (0.50) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL25028651 | 0.85 | GSK3B (0.50) | GSK3BDYRK1ANFATC1ARSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |