SCHEMBL25029052

SCHEMBL25029052

Cc1nc(-c2c[nH]c3c(S(C)(=O)=O)cccc23)ccc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.44
▸ GAA P10253 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ DYRK1B Q9Y463 1/20 0.44
▸ AR P10275 9/20 0.43
▸ DYRK1A Q13627 4/20 0.41
▸ GSK3B P49841 4/20 0.41
▸ NFATC1 O95644 2/20 0.41
▸ CLK1 P49759 2/20 0.41
▸ CDK5 Q00535 2/20 0.41
▸ CDK5R1 Q15078 2/20 0.41
▸ CCNT1 O60563 2/20 0.39
▸ CCNK O75909 2/20 0.39
▸ CCNE1 P24864 2/20 0.39
▸ CDK2 P24941 2/20 0.39
▸ CDK9 P50750 2/20 0.39
▸ CDK12 Q9NYV4 2/20 0.39
▸ CDK7 P50613 2/20 0.39
▸ CCNH P51946 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25029300 0.81 AR (0.63) MEN1GAARAB9AKMT2AAR
SCHEMBL25029186 0.79 AR (0.55) MEN1GAARAB9AKMT2AAR
SCHEMBL25029237 0.79 DYRK1A (0.64) MEN1GAARAB9AKMT2AAR
SCHEMBL29363909 0.79 AR (0.55) MEN1GAARAB9AKMT2AAR
SCHEMBL29363479 0.78 AR (0.51) MEN1GAARAB9AKMT2AAR
SCHEMBL25029294 0.78 AR (0.51) MEN1GAARAB9AKMT2AAR
SCHEMBL25028849 0.76 AR (0.58) MEN1GAARAB9AKMT2AAR
SCHEMBL29364174 0.76 AR (0.58) MEN1GAARAB9AKMT2AAR
SCHEMBL25029184 0.76 DYRK1A (0.66) MEN1GAARAB9AKMT2AAR
SCHEMBL25029225 0.75 AR (0.43) MEN1GAARAB9AKMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 — — US disclosed
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-04-17 — — US disclosed
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2025-03-20 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
EP-4182320-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2023-05-24 — — EP disclosed
CN-115996926-A Indole compounds as androgen receptor modulators 尼多生物科学有限公司 2023-04-21 — — CN disclosed
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-16 — — US disclosed
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-16 — — US disclosed
WO-2022020342-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2022-01-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2818/4885GAA 2814/4885RAB9A 2811/4885
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2673/4885GAA 2947/4885RAB9A 2639/4885
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2818/4885GAA 2814/4885RAB9A 2811/4885
US-11667624-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 MEN1 2646/4885GAA 2539/4885RAB9A 2744/4885
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2818/4885GAA 2814/4885RAB9A 2811/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 MEN1 2646/4885GAA 2539/4885RAB9A 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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