Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029294 | 1.00 | AR (0.51) | ARBRPF1MEN1GAARAB9A | |
| SCHEMBL25027616 | 0.89 | AR (0.62) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL29363869 | 0.89 | AR (0.62) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL25029300 | 0.81 | AR (0.63) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL25029186 | 0.79 | AR (0.55) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL29363909 | 0.79 | AR (0.55) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL25029237 | 0.79 | DYRK1A (0.64) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL25029052 | 0.78 | MEN1 (0.44) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL25028849 | 0.76 | AR (0.58) | ARMEN1GAARAB9AKMT2A | |
| SCHEMBL25029184 | 0.76 | DYRK1A (0.66) | ARMEN1GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |