SCHEMBL25029153

SCHEMBL25029153

Cc1nc(Br)cnc1OC1CCN(C)C1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 2/20 0.38
▸ PIK3CA P42336 2/20 0.38
▸ PIK3CB P42338 2/20 0.38
▸ PIK3CG P48736 2/20 0.38
▸ LRRK2 Q5S007 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ CHRM4 P08173 1/20 0.38
▸ CHRM5 P08912 1/20 0.38
▸ CHRM1 P11229 1/20 0.38
▸ CHRM3 P20309 1/20 0.38
▸ CNR2 P34972 1/20 0.35
▸ NOS3 P29474 1/20 0.35
▸ NOS1 P29475 1/20 0.35
▸ NOS2 P35228 1/20 0.35
▸ HTR2C P28335 1/20 0.34
▸ HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14634584 0.87 LRRK2 (0.41) LRRK2CHRM2CHRM4CHRM5CHRM1
SCHEMBL14634583 0.87 LRRK2 (0.41) LRRK2CHRM2CHRM4CHRM5CHRM1
SCHEMBL26713819 0.82 FPR2 (0.33) LRRK2
SCHEMBL25028986 0.82 PIK3CD (0.39) PIK3CD
SCHEMBL25028797 0.81 PIK3CD (0.47) PIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL29005586 0.80 PIK3CD (0.32) PIK3CD
SCHEMBL19575426 0.78 LRRK2 (0.47) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL24439695 0.78 LRRK2 (0.40) LRRK2
SCHEMBL2319533 0.78 CHRM2 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL25029093 0.77 PIK3CD (0.51) PIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 — — US disclosed
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-04-17 — — US disclosed
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2025-03-20 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
EP-4182320-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2023-05-24 — — EP disclosed
CN-115996926-A Indole compounds as androgen receptor modulators 尼多生物科学有限公司 2023-04-21 — — CN disclosed
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-16 — — US disclosed
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-16 — — US disclosed
WO-2022020342-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2022-01-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 PIK3CD 4215/4885PIK3CA 4152/4885PIK3CB 3786/4885
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 PIK3CD 4174/4885PIK3CA 4090/4885PIK3CB 3789/4885
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 PIK3CD 4215/4885PIK3CA 4152/4885PIK3CB 3786/4885
US-11667624-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 PIK3CD 4102/4885PIK3CA 4134/4885PIK3CB 3622/4885
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 PIK3CD 4215/4885PIK3CA 4152/4885PIK3CB 3786/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 PIK3CD 4102/4885PIK3CA 4134/4885PIK3CB 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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