SCHEMBL25030971

SCHEMBL25030971

CC(C)NC1CCS(=N)(=O)CC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8224831 0.82 ALDH1A1 (0.41) POLBALDH1A1MAPT
SCHEMBL21870609 0.75 SMYD3 (0.33)
SCHEMBL2606775 0.74 ALDH1A1 (0.52) POLBALDH1A1MAPT
SCHEMBL26718859 0.74 ALDH1A1 (0.52) POLBALDH1A1MAPT
SCHEMBL18844877 0.73 GAA (0.31)
SCHEMBL18458286 0.72 MDM2 (0.41) ALDH1A1
SCHEMBL16171239 0.72 MDM2 (0.41) ALDH1A1
SCHEMBL2600363 0.72 MDM2 (0.41) ALDH1A1
SCHEMBL681668 0.72
SCHEMBL104716 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023016434-A1 COMPOUNDS TARGETING MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-02-16 WO disclosed