SCHEMBL25031967

SCHEMBL25031967

CCOCCNCCCCC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 12/20 0.51
▸ BRD4 O60885 11/20 0.51
▸ DDB1 Q16531 3/20 0.51
▸ STAT3 P40763 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24068298 0.98 STAT3 (0.52) CRBNBRD4DDB1STAT3
SCHEMBL25029989 0.93 STAT3 (0.54) CRBNBRD4DDB1STAT3
SCHEMBL25031687 0.91 STAT3 (0.53) CRBNBRD4DDB1STAT3
SCHEMBL25031672 0.90 STAT3 (0.51) CRBNBRD4DDB1STAT3
SCHEMBL23766094 0.89 STAT3 (0.52) CRBNBRD4DDB1STAT3
SCHEMBL25030007 0.89 STAT3 (0.54) CRBNBRD4DDB1STAT3
SCHEMBL25782017 0.88 CRBN (0.52) CRBNBRD4DDB1STAT3
SCHEMBL26321021 0.88 CRBN (0.64) CRBNBRD4DDB1
SCHEMBL25031675 0.87 CRBN (0.53) CRBNBRD4DDB1
SCHEMBL23766284 0.87 CRBN (0.53) CRBNBRD4DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134104-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM Eubulus Biotherapeutics Inc. (CN) 2023-02-15 — — EP disclosed
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