Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 12/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030007 | 0.97 | STAT3 (0.54) | STAT3BRD4CRBNDDB1 | |
| SCHEMBL25031671 | 0.93 | STAT3 (0.56) | STAT3BRD4CRBNDDB1 | |
| SCHEMBL25031775 | 0.93 | BRD4 (0.55) | BRD4CRBNDDB1 | |
| SCHEMBL24068298 | 0.92 | STAT3 (0.52) | STAT3BRD4CRBNDDB1 | |
| SCHEMBL25031967 | 0.91 | CRBN (0.51) | STAT3BRD4CRBNDDB1 | |
| SCHEMBL25031672 | 0.89 | STAT3 (0.51) | STAT3BRD4CRBNDDB1 | |
| SCHEMBL23766094 | 0.88 | STAT3 (0.52) | STAT3BRD4CRBNDDB1 | |
| SCHEMBL25031675 | 0.86 | CRBN (0.53) | BRD4CRBNDDB1HDAC1 | |
| SCHEMBL23766284 | 0.86 | CRBN (0.53) | BRD4CRBNDDB1HDAC1 | |
| SCHEMBL26323874 | 0.86 | CRBN (0.63) | BRD4CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |