Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 8/20 | 0.37 |
| ▸ | PPARD | Q03181 | 8/20 | 0.37 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270507 | 1.00 | HTR6 (0.39) | HTR6PIK3C3CA12CA1CA7 | |
| SCHEMBL22111128 | 0.84 | PPARG (0.45) | HTR6PPARGPPARDPPARAMEN1 | |
| SCHEMBL29783676 | 0.84 | PPARG (0.45) | HTR6PPARGPPARDPPARAMEN1 | |
| SCHEMBL29783668 | 0.79 | HTR6 (0.53) | HTR6PPARGPPARDPPARAHDAC3 | |
| SCHEMBL20742940 | 0.79 | HTR6 (0.53) | HTR6PPARGPPARDPPARAHDAC3 | |
| SCHEMBL29212344 | 0.76 | HTR6 (0.40) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30184592 | 0.74 | HTR6 (0.44) | HTR6MEN1KMT2A | |
| SCHEMBL25032365 | 0.74 | HTR6 (0.44) | HTR6MEN1KMT2A | |
| SCHEMBL29212327 | 0.73 | HTR6 (0.43) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31270117 | 0.73 | HTR6 (0.35) | HTR6PIK3C3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |