Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184460 | 1.00 | CA12 (0.33) | CA12CA1CA2CA9MAOA | |
| SCHEMBL25030907 | 0.81 | LMNA (0.35) | MAOAMAPT | |
| SCHEMBL30184470 | 0.81 | LMNA (0.35) | MAOAMAPT | |
| SCHEMBL30184621 | 0.78 | — | — | |
| SCHEMBL25033173 | 0.78 | — | — | |
| SCHEMBL25033178 | 0.77 | — | — | |
| SCHEMBL30184507 | 0.77 | — | — | |
| SCHEMBL23144024 | 0.72 | CA12 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL23144425 | 0.71 | PLK1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL29811759 | 0.71 | PLK1 (0.41) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |