Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25032715 | 0.83 | CA2 (0.39) | CA1CA2CA9ALDH1A1PTGS1 | |
| SCHEMBL23144259 | 0.80 | CA2 (0.55) | CA1CA2CA9ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7048906 | 0.77 | CA1 (0.56) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL2007287 | 0.72 | POLB (0.70) | CA1CA2CA9CA12LMNA | |
| SCHEMBL2342564 | 0.72 | CA1 (0.49) | CA1CA2CA9HPGDCA12 | |
| SCHEMBL17476037 | 0.71 | POLB (0.68) | CA1CA2CA9CA12LMNA | |
| Potassium SCHEMBL29831526 | 0.71 | POLB (0.68) | CA1CA2CA9CA12LMNA | |
| Potassium SCHEMBL17476038 | 0.71 | POLB (0.68) | CA1CA2CA9CA12LMNA | |
| SCHEMBL28110073 | 0.71 | CA1 (0.47) | CA1CA2CA9CA12GAA | |
| SCHEMBL25032711 | 0.70 | CA1 (0.41) | CA1CA2CA9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |