Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475476 | 1.00 | CRBN (0.41) | CRBNDDB1HRH3POLBFFAR4 | |
| SCHEMBL24670689 | 0.89 | CRBN (0.44) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30475505 | 0.85 | CRBN (0.48) | CRBNDDB1HRH3POLB | |
| SCHEMBL25823256 | 0.85 | CRBN (0.48) | CRBNDDB1HRH3POLB | |
| SCHEMBL25035108 | 0.85 | CRBN (0.44) | CRBNDDB1HRH3POLB | |
| SCHEMBL25819400 | 0.84 | GAA (0.37) | HRH3FFAR4 | |
| SCHEMBL25935225 | 0.84 | CRBN (0.43) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL31382367 | 0.83 | CRBN (0.47) | CRBNDDB1POLBFFAR4GSPT1 | |
| SCHEMBL25031309 | 0.82 | CRBN (0.43) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25029440 | 0.82 | CRBN (0.51) | CRBNDDB1HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018238-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |