Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 13/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.61 |
| ▸ | USP2 | O75604 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | CLK1 | P49759 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882833 | 1.00 | ALDH1A1 (0.62) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29979063 | 0.84 | STING1 (0.49) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL25138317 | 0.84 | STING1 (0.49) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30882842 | 0.83 | STING1 (0.57) | POLBMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL25037406 | 0.83 | STING1 (0.57) | POLBMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL25037514 | 0.81 | STING1 (0.51) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30191392 | 0.81 | STING1 (0.51) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL25037517 | 0.81 | STING1 (0.46) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30191932 | 0.81 | STING1 (0.46) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL25037515 | 0.81 | MAPT (0.50) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |