Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25036235 | 0.86 | DDB1 (0.55) | DDB1CRBNOPRM1CCR5 | |
| SCHEMBL25036801 | 0.85 | CRBN (0.57) | DDB1CRBNOPRL1OPRM1 | |
| SCHEMBL27452842 | 0.82 | CRBN (0.42) | DDB1CRBNOPRM1 | |
| SCHEMBL23540861 | 0.80 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL23541289 | 0.80 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL31068515 | 0.80 | DDB1 (0.51) | DDB1CRBNOPRL1OPRM1 | |
| SCHEMBL23541270 | 0.80 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL23540339 | 0.79 | DDB1 (0.41) | DDB1CRBN | |
| SCHEMBL22502648 | 0.79 | DDB1 (0.57) | DDB1CRBNHTR4 | |
| SCHEMBL20845888 | 0.79 | CRBN (0.72) | DDB1CRBNOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |