Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.55 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25036211 | 0.86 | DDB1 (0.53) | DDB1CRBNOPRM1CCR5 | |
| SCHEMBL30273466 | 0.86 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL27178155 | 0.86 | DDB1 (0.50) | DDB1CRBNGPR119 | |
| SCHEMBL29751542 | 0.84 | DDB1 (0.48) | DDB1CRBNOPRM1OPRD1OGFRL1 | |
| SCHEMBL24607628 | 0.84 | DDB1 (0.48) | DDB1CRBNOPRM1OPRD1OGFRL1 | |
| SCHEMBL25036248 | 0.83 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL21071066 | 0.81 | DDB1 (0.52) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL26101564 | 0.81 | DDB1 (0.47) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL26097555 | 0.81 | DDB1 (0.47) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL30796701 | 0.81 | DDB1 (0.50) | DDB1CRBNPRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |