Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | IL1B | P01584 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23884307 | 0.90 | CRBN (0.56) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL23884304 | 0.90 | CRBN (0.56) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL23884126 | 0.90 | CRBN (0.56) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL21997220 | 0.89 | CRBN (0.57) | DDB1CRBNSTAT3TNFIL1B | |
| SCHEMBL23884183 | 0.89 | DDB1 (0.57) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL21997506 | 0.88 | DDB1 (0.58) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL29942621 | 0.88 | DDB1 (0.55) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL23302001 | 0.88 | DDB1 (0.55) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL25507852 | 0.86 | CRBN (0.55) | DDB1CRBNPIK3CATNFIL1B | |
| SCHEMBL25036210 | 0.85 | CRBN (0.54) | DDB1CRBNTNFIL1BIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |