Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30274041 | 0.90 | PTPN1 (0.46) | PTPN1GRM6ACLYMAPTLMNA | |
| SCHEMBL25034776 | 0.89 | PTPN1 (0.47) | PTPN1GRM6ACLYMAPTLMNA | |
| SCHEMBL30273615 | 0.89 | PTPN1 (0.47) | PTPN1GRM6ACLYMAPTLMNA | |
| SCHEMBL25034892 | 0.86 | PTPN1 (0.35) | PTPN1GRM6ACLYMAPTLMNA | |
| SCHEMBL30274011 | 0.84 | PTPN1 (0.43) | PTPN1GRM6KMT2AMAPTLMNA | |
| SCHEMBL25036178 | 0.83 | PTPN1 (0.44) | PTPN1GRM6GAAKMT2AMAPT | |
| SCHEMBL30273913 | 0.83 | PTPN1 (0.44) | PTPN1GRM6GAAKMT2AMAPT | |
| SCHEMBL30273918 | 0.83 | PTPN1 (0.44) | PTPN1GRM6GAAKMT2AMAPT | |
| SCHEMBL25036186 | 0.83 | PTPN1 (0.45) | PTPN1GRM6GAAKMT2AMAPK14 | |
| SCHEMBL30274194 | 0.83 | PTPN1 (0.45) | PTPN1GRM6GAAKMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |