Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | LHCGR | P22888 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034776 | 1.00 | PTPN1 (0.47) | PTPN1GRM6ALOX5APFEN1LHCGR | |
| SCHEMBL25036186 | 0.94 | PTPN1 (0.45) | PTPN1GRM6ALOX5APFEN1ACLY | |
| SCHEMBL30274194 | 0.94 | PTPN1 (0.45) | PTPN1GRM6ALOX5APFEN1ACLY | |
| SCHEMBL30273918 | 0.92 | PTPN1 (0.44) | PTPN1GRM6MAPTLMNAHPGD | |
| SCHEMBL25036178 | 0.92 | PTPN1 (0.44) | PTPN1GRM6MAPTLMNAHPGD | |
| SCHEMBL30273913 | 0.92 | PTPN1 (0.44) | PTPN1GRM6MAPTLMNAHPGD | |
| SCHEMBL25036303 | 0.90 | PTPN1 (0.45) | PTPN1GRM6LHCGRMAPTHPGD | |
| SCHEMBL25036712 | 0.90 | PTPN1 (0.45) | PTPN1GRM6ALOX5APFEN1ACLY | |
| SCHEMBL25036333 | 0.90 | PTPN1 (0.48) | PTPN1GRM6ALOX5APFEN1LHCGR | |
| SCHEMBL25036613 | 0.89 | PTPN1 (0.36) | PTPN1GRM6ACLYMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC | 2025-10-02 | — | — | US | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | PTPN1, PTPN2, PTPN18 | PTPN1 1/4885GRM6 2008/4885ALOX5AP 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.