Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30037969 | 1.00 | WRN (0.48) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL25037298 | 0.94 | WRN (0.49) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL30038779 | 0.94 | WRN (0.49) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL25037113 | 0.92 | WRN (0.56) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL31387134 | 0.91 | WRN (0.54) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL25037157 | 0.88 | WRN (0.49) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL30038247 | 0.88 | WRN (0.49) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL31387135 | 0.88 | WRN (0.46) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| Hydrochloric Acid SCHEMBL31387155 | 0.87 | WRN (0.46) | WRNALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL25037179 | 0.87 | WRN (0.47) | WRNALDH1A1GAABRAFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046859-A1 | Bicyclic Compounds and their Uses | NOVARTIS PHARMA AG (CH) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230046859-A1 | Bicyclic Compounds and their Uses | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C1R, F12 | WRN 1829/4885ALDH1A1 2542/4885SMN1; SMN2 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.