Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31387155 | 0.99 | WRN (0.46) | WRNMAPTTHRBNPSR1HSD17B10 | |
| SCHEMBL30037511 | 0.93 | WRN (0.48) | WRNMAPTNPSR1HSD17B10MAPK9 | |
| SCHEMBL25036821 | 0.93 | WRN (0.48) | WRNMAPTNPSR1HSD17B10MAPK9 | |
| SCHEMBL31384779 | 0.92 | WRN (0.54) | WRNMAPTNPSR1MAPK9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31270598 | 0.91 | WRN (0.53) | WRNMAPTNPSR1MAPK9ALDH1A1 | |
| SCHEMBL31387245 | 0.88 | WRN (0.41) | WRNMAPTHSD17B10LMNAAKR1B1 | |
| SCHEMBL30037969 | 0.88 | WRN (0.48) | WRNMAPTNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL25036677 | 0.88 | WRN (0.48) | WRNMAPTNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL31500029 | 0.87 | WRN (0.47) | WRNMAPTNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL31394422 | 0.86 | WRN (0.41) | WRNMAPTTHRBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |