Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273817 | 0.86 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL25036968 | 0.86 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30274113 | 0.86 | CDK7 (0.43) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL22836102 | 0.85 | DDB1 (0.48) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL31160909 | 0.85 | DDB1 (0.48) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30273425 | 0.84 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL23541275 | 0.84 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL23541145 | 0.83 | CDK7 (0.44) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL25036367 | 0.83 | DDB1 (0.44) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30273873 | 0.83 | DDB1 (0.44) | DDB1CRBNCDK7CDK13CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |