Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30191475 | 1.00 | STING1 (0.50) | STING1ALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL25037356 | 0.94 | STING1 (0.52) | STING1ALDH1A1MAPTRAB9A | |
| SCHEMBL30191182 | 0.94 | STING1 (0.52) | STING1ALDH1A1MAPTRAB9A | |
| SCHEMBL30191040 | 0.94 | STING1 (0.50) | STING1ALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL25037402 | 0.94 | STING1 (0.50) | STING1ALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL25037357 | 0.91 | STING1 (0.54) | STING1ALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL30191544 | 0.91 | STING1 (0.54) | STING1ALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL25037405 | 0.86 | STING1 (0.52) | STING1MAPT | |
| SCHEMBL30882843 | 0.86 | STING1 (0.52) | STING1MAPT | |
| SCHEMBL25035495 | 0.85 | MAPT (0.48) | STING1ALDH1A1KDM4EMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |