Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13438908 | 1.00 | CA1 (0.39) | CA1CA2GAAEPHX1EPHX2 | |
| SCHEMBL11935230 | 1.00 | CA1 (0.39) | CA1CA2GAAEPHX1EPHX2 | |
| SCHEMBL25039281 | 0.91 | CA1 (0.38) | CA1CA2GAAEPHX1EPHX2 | |
| SCHEMBL30279113 | 0.86 | CNR2 (0.37) | GAAALDH1A1ALDH3A1CARM1PRMT6 | |
| SCHEMBL25041882 | 0.86 | CNR2 (0.37) | GAAALDH1A1ALDH3A1CARM1PRMT6 | |
| SCHEMBL25039268 | 0.86 | CA1 (0.43) | CA1CA2GAAEPHX1EPHX2 | |
| SCHEMBL25039266 | 0.85 | CA1 (0.40) | CA1CA2GAAEPHX1EPHX2 | |
| SCHEMBL13439172 | 0.84 | LIPC (0.46) | CA1CA2CNR2 | |
| SCHEMBL11935145 | 0.84 | LIPC (0.46) | CA1CA2CNR2 | |
| SCHEMBL11935225 | 0.81 | MAPT (0.45) | GAAALDH1A1ALDH3A1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |