Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3
The experimentally established mechanism targets of Epinephrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 7/20 | 1.00 |
| ▸ | ADRB1 known ✓ | P08588 | 6/20 | 0.96 |
| ▸ | ADRB3 known ✓ | P13945 | 5/20 | 0.96 |
| ▸ | ADRA2A known ✓ | P08913 | 3/20 | 0.96 |
| ▸ | ADRA2B known ✓ | P18089 | 3/20 | 0.96 |
| ▸ | ADRA2C known ✓ | P18825 | 3/20 | 0.96 |
| ▸ | ADRA1A known ✓ | P35348 | 3/20 | 0.96 |
| ▸ | ADRA1B known ✓ | P35368 | 3/20 | 0.96 |
| ▸ | ADRA1D known ✓ | P25100 | 2/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | BLM | P54132 | 5/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.96 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.96 |
| ▸ | MAPT | P10636 | 6/20 | 0.96 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.96 |
| ▸ | TSHR | P16473 | 5/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.96 |
| ▸ | MEN1 | O00255 | 3/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racepinephrine SCHEMBL16667632 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL41370 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL31238229 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL9614373 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL31267207 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL4980185 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| L-Adrenaline SCHEMBL4983607 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL28311143 | 0.98 | KDM4E (0.96) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL3111795 | 0.98 | KDM4E (0.96) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL660960 | 0.98 | KDM4E (0.96) | KDM4EADRB2BLMPMP22NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13593 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3869192-B1 | METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE | HUMAN METABOLOMICS INST INC (CN) | 2026-05-13 | — | — | EP | claimed |
| CN-122005425-A | Epinephrine soluble microneedle, preparation method and application thereof, and transdermal patch | 北京医院 | 2026-05-12 | — | — | CN | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-3723819-B1 | WOUND DRESSING | ANIMAL ETHICS PTY LTD (AU) | 2026-04-22 | — | — | EP | claimed |
| EP-3931568-B1 | AN ELECTROCHEMICAL SENSING APPROACH FOR MOLECULE QUANTIFICATION IN BODY FLUIDS | CALIFORNIA INST OF TECHN (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4554640-B1 | AUTOINJECTOR | ALK ABELLO AS (DK) | 2026-04-08 | — | — | EP | claimed |
| EP-4007921-B1 | METHOD OF DETERMINING RISK FOR CHRONIC STRESS AND STROKE | UNIV NORTHWEST (ZA) | 2026-03-25 | — | — | EP | claimed |
| EP-4706649-A1 | USE OF ADRENALIN FOR THE TREATMENT OF SHOCKS | BIOPROJET (FR) | 2026-03-11 | — | — | EP | claimed |
| US-20260014180-A1 | BIOACTIVES AND THEIR USES | AREPA IP LTD (NZ) | 2026-01-15 | — | — | US | claimed |
| EP-3781315-B1 | MICROFLUIDIC METHOD FOR SINGLE CELL ANALYSIS | HIFIBIO SAS (FR) | 2026-01-14 | — | — | EP | claimed |
| EP-0092200-B1 | RESORBABLE SHEET FOR CLOSING AND HEALING WOUNDS, AND PROCESS FOR ITS PRODUCTION | Serapharm GmbH & Co. KG (DE) | 1988-11-30 | — | — | EP | claimed |
| CN-87104499-A | Novel alginic acid esters | — | 1988-04-06 | — | — | CN | claimed |
| EP-0251905-A2 | Esters of alginic acid | FIDIA S.p.A. (IT) | 1988-01-07 | — | — | EP | claimed |
| EP-0216453-A2 | Esters of hyaluronic acid and their salts. | FIDIA S.p.A. (IT) | 1987-04-01 | — | — | EP | claimed |
| EP-0213108-A2 | Pharmaceutical preparation containing an antihypotonic as the active agent | Burghart, Kurt, Dr. (DE) | 1987-03-04 | — | — | EP | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0092200-A2 | Resorbable sheet for closing and healing wounds, and process for its production | Serapharm GmbH & Co. KG (DE) | 1983-10-26 | — | — | EP | claimed |
| EP-0076996-A1 | Carboxylic-acid derivatives, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1983-04-20 | — | — | EP | claimed |
| US-4275074-A | Catecholamine treatment of ocular hypertension | Dobbie, Graham J. (US) | 1981-06-23 | — | — | US | claimed |
| US-3981398-A | Aid in the management of clinical emergencies in medical and dental practices and other circumstances | Pienaar, Hendrik Lukas (ZA) | 1976-09-21 | — | — | US | claimed |