Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3
The experimentally established mechanism targets of Epinephrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 7/20 | 1.00 |
| ▸ | ADRB1 known ✓ | P08588 | 6/20 | 0.96 |
| ▸ | ADRB3 known ✓ | P13945 | 5/20 | 0.96 |
| ▸ | ADRA2A known ✓ | P08913 | 3/20 | 0.96 |
| ▸ | ADRA2B known ✓ | P18089 | 3/20 | 0.96 |
| ▸ | ADRA2C known ✓ | P18825 | 3/20 | 0.96 |
| ▸ | ADRA1A known ✓ | P35348 | 3/20 | 0.96 |
| ▸ | ADRA1B known ✓ | P35368 | 3/20 | 0.96 |
| ▸ | ADRA1D known ✓ | P25100 | 2/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | BLM | P54132 | 5/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.96 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.96 |
| ▸ | MAPT | P10636 | 6/20 | 0.96 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.96 |
| ▸ | TSHR | P16473 | 5/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.96 |
| ▸ | MEN1 | O00255 | 3/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racepinephrine SCHEMBL16667632 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL41370 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL31238229 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL9614373 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL31267207 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL25041 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| L-Adrenaline SCHEMBL4983607 | 1.00 | KDM4E (1.00) | KDM4EADRB2BLMPMP22NPSR1 | |
| Racepinephrine SCHEMBL28311143 | 0.98 | KDM4E (0.96) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL3111795 | 0.98 | KDM4E (0.96) | KDM4EADRB2BLMPMP22NPSR1 | |
| Epinephrine SCHEMBL660960 | 0.98 | KDM4E (0.96) | KDM4EADRB2BLMPMP22NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110432225-B | Construction method of animal model combining blood stasis phlegm coagulation and laryngeal cancer | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2021-10-22 | — | — | CN | claimed |
| CN-113332239-A | Adrenaline hydrochloride injection and preparation method thereof | 上海葆隆生物科技有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-110432225-A | The construction method of blood stasis phlegm solidifying card and laryngocarcinoma Disease Syndrome integrated animal model | GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE SECOND AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF C | 2019-11-12 | — | — | CN | claimed |
| CN-110433008-A | A method of injection mitigates eye pouch | QINGYANG YIMEI TECH BEIJING CO LTD | 2019-11-12 | — | — | CN | claimed |
| CN-110123263-A | Acute anterior uveitis iris and ciliary body metamorphosis observation method | 李寿庆 | 2019-08-16 | — | — | CN | claimed |
| CN-110100789-A | A method of establishing easy toxicity | 湖南中医药大学 | 2019-08-09 | — | — | CN | claimed |
| CN-109998990-A | A kind of small dimension adrenalin hydrochloride injection and preparation method thereof | 遂成药业股份有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-208823309-U | PICC punctures multiufunctional therapeutic vehicle | 南方医科大学南方医院 | 2019-05-07 | — | — | CN | claimed |
| CN-106727462-B | A kind of drug that treating facial dermatitis and its application | 四川省人民医院 | 2019-04-09 | — | — | CN | claimed |
| CN-109528645-A | A kind of children's adrenalin hydrochloride injection and preparation method thereof | 遂成药业股份有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-102335125-A | Adrenaline hydrochloride injection and preparation process thereof | SHANGHAI HARVEST PHARMACEUTICAL CO LTD | 2012-02-01 | — | — | CN | claimed |
| CN-100345550-C | Compound eye drops for treating electro-optic harmed eye | WANG KEQIANG (CN) | 2007-10-31 | — | — | CN | claimed |
| CN-1285363-C | Chinese and western compound medicinal eye drop for quick treatment of eyeball congestion disease | TAN BANGYONG (CN) | 2006-11-22 | — | — | CN | claimed |
| CN-1823797-A | Compound eye drops for treating electro-optic harmed eye | WANG KEQIANG (CN) | 2006-08-30 | — | — | CN | claimed |
| CN-1704077-A | Chinese and western compound medicinal eye drop for quick treatment of eyeball congestion disease | TAN BANGYONG (CN) | 2005-12-07 | — | — | CN | claimed |
| CN-1101181-C | Composition for treating hemorrhoids and application thereof | WYETH CORP (US) | 2003-02-12 | — | — | CN | claimed |
| CN-1048393-C | Aqueous drug composition having property of reversible thermosetting gelation | WAKAMOTO PHARMA CO LTD (JP) | 2000-01-19 | — | — | CN | claimed |
| CN-1171045-A | Compositions for treating hemorrhoids and methods of use thereof | WHITEHALL LAB LTD (GB) | 1998-01-21 | — | — | CN | claimed |
| CN-1097593-A | Aqueous drug composition having property of reversible thermosetting gelation | WAKAMOTO PHARMA CO LTD (JP) | 1995-01-25 | — | — | CN | claimed |
| CN-1093897-A | The preparation method of surface anesthesia film | MENG LIJUN (CN) | 1994-10-26 | — | — | CN | claimed |