Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.34 |
| ▸ | CDK9 | P50750 | 6/20 | 0.34 |
| ▸ | CDK4 | P11802 | 4/20 | 0.34 |
| ▸ | CCND1 | P24385 | 4/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | CCNH | P51946 | 2/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039795 | 0.95 | HRH4 (0.38) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25039932 | 0.88 | KMT2A (0.40) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25040044 | 0.88 | KMT2A (0.40) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25039945 | 0.88 | KMT2A (0.40) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25042095 | 0.85 | IRAK1 (0.32) | HRH4 | |
| SCHEMBL25041915 | 0.85 | HRH4 (0.36) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25041906 | 0.85 | HRH4 (0.36) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25041392 | 0.84 | HRH4 (0.37) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL25039881 | 0.83 | HRH4 (0.38) | HRH4CCNT1CDK9CDK4CCND1 | |
| SCHEMBL30279078 | 0.81 | IRAK1 (0.31) | HRH4TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |