Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25040044 | 1.00 | KMT2A (0.40) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25039932 | 1.00 | KMT2A (0.40) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25039925 | 0.93 | ALDH1A1 (0.39) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25039905 | 0.93 | ALDH1A1 (0.39) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25041780 | 0.90 | KDM4E (0.34) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25041783 | 0.90 | KDM4E (0.34) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25039866 | 0.90 | KDM4E (0.34) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25039985 | 0.89 | SCN10A (0.33) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25042096 | 0.89 | KMT2A (0.41) | KMT2AALDH1A1KDM4EGAAHRH4 | |
| SCHEMBL25041373 | 0.88 | HRH4 (0.38) | HRH4CCNT1CDK4CCND1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |