Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 9/20 | 0.33 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279107 | 1.00 | SPHK1 (0.41) | SPHK1S1PR1PDGFRACCNE1CDK2 | |
| SCHEMBL25039261 | 0.86 | SMYD3 (0.41) | CNR2CNR1 | |
| SCHEMBL29218672 | 0.82 | CNR2 (0.37) | SPHK1S1PR1CNR2CNR1EPHX1 | |
| SCHEMBL30278983 | 0.81 | HTT (0.38) | SPHK1S1PR1PDGFRACCNE1CDK2 | |
| SCHEMBL25041527 | 0.81 | HTT (0.38) | SPHK1S1PR1PDGFRACCNE1CDK2 | |
| SCHEMBL25041556 | 0.80 | CNR2 (0.41) | CNR2CNR1EPHX1EPHX2 | |
| SCHEMBL31206125 | 0.80 | CNR2 (0.41) | CNR2CNR1EPHX1EPHX2 | |
| SCHEMBL29218860 | 0.77 | S1PR1 (0.39) | SPHK1S1PR1CNR2CNR1 | |
| SCHEMBL29218877 | 0.77 | SPHK1 (0.38) | SPHK1S1PR1 | |
| SCHEMBL25039336 | 0.76 | SPHK1 (0.64) | SPHK1EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |