Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.41 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279107 | 0.86 | SPHK1 (0.41) | CNR2CNR1 | |
| SCHEMBL25041540 | 0.86 | SPHK1 (0.41) | CNR2CNR1 | |
| SCHEMBL25039410 | 0.81 | KIT (0.40) | SMYD3CNR2NR1H4FLT3CHEK1 | |
| SCHEMBL25042151 | 0.80 | ROCK2 (0.40) | CNR2NR1H4FLT3KITCNR1 | |
| SCHEMBL25040034 | 0.80 | NR1H4 (0.44) | CNR2NR1H4 | |
| SCHEMBL25041798 | 0.79 | KDM1A (0.43) | — | |
| SCHEMBL25041982 | 0.78 | SMYD3 (0.40) | SMYD3FLT3KIT | |
| SCHEMBL25039462 | 0.77 | CHEK1 (0.38) | CNR2NR1H4FLT3CHEK1KIT | |
| SCHEMBL30279151 | 0.77 | CHEK1 (0.38) | CNR2NR1H4FLT3CHEK1KIT | |
| SCHEMBL30278983 | 0.76 | HTT (0.38) | CNR2FLT3KITCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-31 | — | — | US | disclosed |
| EP-4384493-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2024-06-19 | — | — | EP | disclosed |
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | SMYD3 3862/4885CNR2 3207/4885NR1H4 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.