SCHEMBL25041772

SCHEMBL25041772

C=C(C#CC(C)(C)N(C)C)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25039080 0.74 LMNA (0.35) LMNAKDM4E
SCHEMBL2442548 0.65 LMNA (0.39) LMNAKDM4E
SCHEMBL23295353 0.65 LMNA (0.39) LMNAKDM4E
SCHEMBL24127548 0.65 LMNA (0.39) LMNA
SCHEMBL15165104 0.64 LMNA (0.42) LMNAKDM4E
SCHEMBL23894132 0.64 LMNA (0.34) LMNA
SCHEMBL2442544 0.64 LMNA (0.38) LMNA
SCHEMBL23894127 0.64 LMNA (0.38) LMNA
SCHEMBL9131597 0.63
SCHEMBL23000888 0.62 LMNA (0.37) LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023015559-A1 MACROCYCLE COMPOUNDS AS INHIBITORS OF RAS NUTSHELL BIOTECH (SHANGHAI) CO., LTD. (CN) 2023-02-16 WO disclosed