Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042158 | 0.88 | PTGER4 (0.36) | LMNATSHRKDM4EALDH1A1PTGER4 | |
| SCHEMBL30279042 | 0.88 | PTGER4 (0.36) | LMNATSHRKDM4EALDH1A1PTGER4 | |
| SCHEMBL13439115 | 0.81 | PTGER4 (0.30) | PTGER4 | |
| SCHEMBL25039761 | 0.81 | MEN1 (0.36) | KDM4CLMNANPC1ALOX15TSHR | |
| SCHEMBL17090158 | 0.81 | NPY5R (0.35) | LMNAKDM4EBRD4 | |
| SCHEMBL13565437 | 0.81 | NPY5R (0.35) | LMNAKDM4EBRD4 | |
| SCHEMBL25042433 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1ASPHRIOX2KDM8 | |
| SCHEMBL30279292 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1PTGER4GAASMN1; SMN2 | |
| SCHEMBL25040029 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1PTGER4GAASMN1; SMN2 | |
| SCHEMBL13439151 | 0.78 | KDM4E (0.35) | KDM4EPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |