Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042437 | 0.87 | KMT2A (0.48) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL18436950 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL18436315 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL25042096 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL25040044 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL25039932 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL25039945 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL17128373 | 0.78 | KMT2A (0.48) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL25039838 | 0.77 | KMT2A (0.50) | KMT2AALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL17128158 | 0.77 | KMT2A (0.50) | KMT2AALDH1A1KDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |