Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 3/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17926033 | 0.83 | F10 (0.43) | TSHRDPP4 | |
| SCHEMBL31436243 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2DRD4MAPK1PDE1APDE1B | |
| SCHEMBL31495468 | 0.78 | GAA (0.48) | SMN1; SMN2GRM2GAACMA1DPP4 | |
| Hydrochloric Acid SCHEMBL31570652 | 0.77 | GAA (0.47) | SMN1; SMN2GRM2GAACMA1DPP4 | |
| Hydrochloric Acid SCHEMBL30713220 | 0.77 | GAA (0.47) | SMN1; SMN2GRM2GAACMA1DPP4 | |
| SCHEMBL27106825 | 0.77 | DPP4 (0.46) | GRM2GAACMA1DPP4MMP1 | |
| SCHEMBL31436236 | 0.76 | CMA1 (0.51) | SMN1; SMN2PDE1APDE1BPDE1CCMA1 | |
| SCHEMBL3611571 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2GRM2MAPK1GAAPDE1A | |
| SCHEMBL3610793 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2GRM2MAPK1GAAPDE1A | |
| SCHEMBL13547191 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2GRM2MAPK1GAAPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |