Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | PDE1A | P54750 | 3/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25043915 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2CMA1PDE1APDE1BPDE1C | |
| SCHEMBL31436236 | 0.81 | CMA1 (0.51) | SMN1; SMN2CMA1POLBL3MBTL1GSK3B | |
| SCHEMBL31436259 | 0.72 | CMA1 (0.49) | SMN1; SMN2CMA1POLBL3MBTL1GSK3B | |
| SCHEMBL8117134 | 0.71 | CMA1 (0.77) | CMA1POLBL3MBTL1GSK3BGSK3A | |
| SCHEMBL9412966 | 0.70 | PDE1B (0.48) | SMN1; SMN2CMA1L3MBTL1GSK3BGSK3A | |
| SCHEMBL5755331 | 0.69 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AALDH1A1MAPTDRD4 | |
| SCHEMBL29839407 | 0.69 | CMA1 (0.58) | SMN1; SMN2CMA1L3MBTL1GSK3BGSK3A | |
| SCHEMBL538147 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2DRD4KDM4ETSHRHIF1A | |
| SCHEMBL3611571 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2CMA1POLBGSK3BGSK3A | |
| SCHEMBL3610793 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2CMA1POLBGSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743459-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025014922-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2025-01-16 | — | — | WO | disclosed |