⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879510 | 0.60 | KDM4E (0.30) | — | |
| SCHEMBL18799919 | 0.54 | — | — | |
| SCHEMBL18721823 | 0.54 | — | — | |
| SCHEMBL22427791 | 0.54 | — | — | |
| SCHEMBL22428055 | 0.54 | — | — | |
| SCHEMBL18799918 | 0.51 | — | — | |
| SCHEMBL1417542 | 0.41 | — | — | |
| SCHEMBL21385109 | 0.38 | — | — | |
| SCHEMBL7770211 | 0.38 | TTR (0.35) | — | |
| Ammonia Solution, Strong SCHEMBL9538468 | 0.38 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230052017-A1 | New compounds for treatment of diseases related to DUX4 expression | Facio Intellectual Property B.V. (NL) | 2023-02-16 | — | — | US | disclosed |