Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666331 | 0.88 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL12121064 | 0.85 | HTT (0.63) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL18382971 | 0.85 | HTT (0.59) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL16658357 | 0.85 | HPGD (0.69) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL12391553 | 0.85 | HTT (0.59) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL25045867 | 0.85 | HPGD (0.60) | SMN1; SMN2HTTPOLBHPGDALDH1A1 | |
| SCHEMBL1032002 | 0.83 | MAPK1 (0.77) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL22071532 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTPOLBHPGDALDH1A1 | |
| SCHEMBL10323669 | 0.82 | HPGD (0.69) | SMN1; SMN2HTTPOLBHPGDALDH1A1 | |
| SCHEMBL5008281 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046065-A1 | MERGING C(sp3)-H ACTIVATION WITH DNA-ENCODING | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-16 | — | — | US | disclosed |