SCHEMBL2504486

SCHEMBL2504486

CN1c2ccccc2Sc2cc(C=Cc3ccc(-c4ccc(C=Cc5ccc6c(c5)Sc5ccccc5N6C)cc4)cc3)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.58
NOX1 Q9Y5S8 6/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MEN1 O00255 1/20 0.56
ADRA2A P08913 1/20 0.56
ADRA2B P18089 1/20 0.56
ADRA2C P18825 1/20 0.56
CHRM3 P20309 1/20 0.56
SLC6A2 P23975 1/20 0.56
HTR2C P28335 1/20 0.56
SLC6A4 P31645 1/20 0.56
DRD3 P35462 1/20 0.56
HTR2B P41595 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 2/20 0.48
LMNA P02545 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
FNTA P49354 4/20 0.45
FNTB P49356 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2504484 1.00 MAOA (0.58) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL15494013 0.86 MAOA (0.59) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL2497091 0.82 HDAC6 (0.43) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL2497092 0.82 HDAC6 (0.43) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL31286280 0.82 MAOA (0.54) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL28332097 0.82 MAOA (0.54) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL7170967 0.82 MAOA (0.73) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL1418367 0.81 MAOA (0.61) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL11592363 0.81 MAOA (0.61) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL30419778 0.81 MAOA (0.61) MAOANOX1L3MBTL1MEN1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817806-B1 PHENOTHAZINES-S-OXIDES AND S,S-DIOXIDES AS hole and excitonblockers for OLEDs BASF SE (DE) 2014-07-30 EP disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
EP-1817806-A1 PHENOTHAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
WO-2006056465-A1 PHENOTHIAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed