Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 14/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.36 |
| ▸ | ESRRA | P11474 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045291 | 0.78 | KDM4E (0.40) | NOTUMRXRAGRIN1GRIN2BESRRA | |
| SCHEMBL30995074 | 0.78 | NOTUM (0.50) | NOTUMESRRA | |
| SCHEMBL25043786 | 0.76 | RXRA (0.38) | NOTUMRXRAGRIN1GRIN2BESRRA | |
| SCHEMBL21623941 | 0.75 | NOTUM (0.40) | NOTUMRXRAGRIN1GRIN2BESRRA | |
| SCHEMBL25043783 | 0.72 | NOTUM (0.42) | NOTUMRXRAGRIN1GRIN2B | |
| SCHEMBL2583097 | 0.71 | NOTUM (0.55) | NOTUM | |
| SCHEMBL25043784 | 0.71 | NOTUM (0.64) | NOTUM | |
| SCHEMBL25045293 | 0.70 | MIF (0.56) | RXRAGRIN1GRIN2B | |
| SCHEMBL30237670 | 0.69 | GRIN1 (0.33) | NOTUMRXRAGRIN1GRIN2BESRRA | |
| SCHEMBL21792049 | 0.68 | NOTUM (1.00) | NOTUMRXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |